SCIENCE

Dr. Frederick vom Saal, PhD. Retired

Dr. Frederick vom Saal, PhD. Retired
University of Missouri, Columbia


Curators distinguished Professor
Emeritus of Biological Sciences

Effects of estrogenic endocrine disrupting chemicals on fetal development.

Research in my laboratory concerns the effects on fetal development of endogenous sex hormones, naturally occurring estrogenic chemicals in food, (such as phytoestrogens in soy), and estrogenic manmade chemicals in consumer products (such as bisphenol A in plastic). We collect fetal mouse reproductive tissues and use primary mouse and human cell culture to investigate cellular mechanisms that mediate responses to hormones and other chemicals. We have confirm observations from in vivo experiments using mice. An important aspect of this research is that we use a physiologically based approach to determine the doses of chemicals that we examine. This approach has led to findings that fetal tissues are extremely sensitive to much lower doses of endogenous estradiol and manmade estrogenic chemicals than had previously been appreciated.

Here is a pdf of Publications, Awards, News - http://biology.missouri.edu/people/?person=203#section-4


Here is Dr. Saal's CV: https://biology.missouri.edu/sites/default/files/people-files/2020-10/2020_vomsaal_cv.pdf 

Here is a showcase of a few researchers who have studied endocrine disruption and other effects of environmental toxins including gender alteration.

Dr. Louis Guillette, PhD

University of North Carolina at Chapel Hill and Medical University of South Carolina
Professor of Obstetrics and Gynecology
Doctorate in Comparative Reproductive Biology
Endowed Chair in Marine Genomics
Professor Howard Hughes Medical Institute
University of Florida Distinguished Professor of Zoology and Associate Dean for Research

Link to Drs. Louis & Elizabeth Guillette's page

Below is a summary of Dr. Warren Porter's list of EPA Omissions in the Safety Registration Process

In other words, these are all the areas that they do NOT test before approving a new chemical.